Hypertension is a common primary care problem with guidelines to help with management, however recent studies have shown there may be important considerations in blood pressure management. Blood pressure varies during different times of day, and one summarized study showed significant benefits to taking blood pressure medications at bedtime on major cardiovascular events. In addition, individual variation in blood pressure may also pose a difference in stroke risk and certain medications address this variation better than others. A systematic review and meta-analysis are summarized that address these issues.
Kim, Jessica MD, "Further Discussion on the Treatment of Hypertension" (2013). Family Medicine Scholarly Works. 10.