Document Type

Evidence Review


Hematologic/Immune, Prevention, Population-based Care

Publication Date



Clinical Question: When should patients be given antibiotics for lyme prophylaxis after a tick bite?

Bottom Line Answer: To provide antibiotic prophylaxis for Lyme disease ALL of these criteria should be met:

  • Tick identified as an adult or nymphal deer tick
  • Attached for > or = 36 hours (by engorgement or time of exposure)
  • Treatment started within 72 hours of tick removal
  • Local rate of infection of ticks with B. Bourgdorferi >=20% (assumed in Vermont)
  • Doxyclycline is not contraindicated

Creative Commons License

Creative Commons Attribution-No Derivative Works 3.0 License
This work is licensed under a Creative Commons Attribution-No Derivative Works 3.0 License.

Included in

Primary Care Commons