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Splenic rupture is a rare, but potentially life-threatening, complication of infectious mononucleosis. Splenic rupture is generally uncommon four weeks after infection onset, however given the long incubation period and prodromal symptomatology characteristic of infectious mono, it can be difficult to determine an individual patient's risk in the clinical setting. Additionally, diagnostic labs have high false negative rates in the first 1-2 weeks of infection. To help alleviate diagnostic uncertainty and protect patients against outcomes such a splenic rupture, an evaluation and consolidation of the available literature yielded a simplified schematic of advisable activity levels for each stage of infection.
Community Health Centers of Burlington
Vermont, Infectious mononucleosis, splenomegaly, return to play
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Medical Education | Primary Care
Barclay, Tessa R., "Determination of Return to Play in Infectious Mononucleosis" (2018). Family Medicine Clerkship Student Projects. 340.