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Proton pump inhibitors (PPIs) are considered the mainstay of medical therapy for gastroesophageal reflux disease (GERD). PPIs have become widely accessible to patients as many of them are currently available over the counter and require no prescription. While PPIs are highly effective at reducing stomach acid, they are not without risks. Short term uses of PPIs are generally well tolerated and involve little risk; however, chronic use of PPIs is associated with significant side effects including diarrhea, impaired B12 absorption, hypomagnesemia, clostridium difficile infection, hip fractures and pneumonia. Currently, the American Academy of Family Physician recommends that PPIs be used only when there is an appropriate diagnosis, at the lowest effective dose and shortest duration of therapy, with a typical regimen lasting 2-12 weeks. Yet even with these guidelines patients are often kept on PPIs for months or years without adequate diagnostic reason. To promote improved PPI management a better understanding of deprescribing and tapering practices amongst primary care physicians must be rendered. The aim of this project is to determine the barriers that prevent PPI deprescribing in cases of GERD.
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Medical Education | Primary Care
Troia, Angela, "PPI Deprescribing Practices for GERD in Primary Care Offices In Western CT" (2020). Family Medicine Clerkship Student Projects. 596.