Date of Completion
Honors College Thesis
Department of Rehabilitation and Movement Science
College of Arts and Science Honors, Honors College
Dr. Sambit Mohapatra
Post-Concussion Syndrome, Diagnosis, Mild traumatic brain injury, Concussion, Brain Injury, Human Behavior, Neurophysiology, Clinical, Neuroscience
INTRODUCTION: Mild traumatic brain injury (mTBI) is caused by an impact or jolt to the head which results in a physiological disruption to the brain. While typically symptoms such as headache, nausea, dizziness, and fatigue subside within the first 2 weeks, a subset of patients fail to recover within this time span and develop prolonged neurophysiological and behavioral symptoms characteristic of post-concussion syndrome (PCS). While there are numerous studies assessing the behavioral and neurophysiological correlates of PCS, there remains a need for these papers to be gathered and reviewed. Therefore, the objective of this paper was to conduct a scoping review of the literature reporting on the neurophysiological and behavioral correlates of patients in the subacute and chronic phase following mTBI. METHODS: MEDLINE/Ovid, Web of Science, CINAHL, Cochrane, and PsycINFO were searched in November 2020 for studies that investigated the neurophysiological and behavioral correlates in the subacute and chronic phase following mTBI. Inclusion and exclusion criteria were determined, and all studies were selected following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement guidelines. RESULTS: In total 336 citations were identified, of which 24 studies were eligible for inclusion in the primary analysis. DISCUSSION: This scoping review suggests a need for a multimodal assessment of mTBI that includes both neurophysiological and behavioral measures. Additionally, more research is needed to further elucidate the progression as well as the neurological underpinnings of PCS.
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Mekkelsen, Ashley Marie, "Neurophysiological and Behavioral Correlates of Post-Concussion Syndrome: A scoping review and validation of methods" (2021). UVM Honors College Senior Theses. 421.
Available for download on Wednesday, May 18, 2022