Date of Completion
Honors College Thesis
Type of Thesis
modularity, robustness, gene regulatory network, evolutionary computation
Modularity has been observed in biological systems of all shapes and sizes. Intuitively, we recognize that this component-based structure can increase efficiency and robustness in a system. Gene regulatory networks are a perfect example of a biological system that exhibits modularity, however, just how this modularity evolved is still unresolved. The research of Espinosa-Soto and Wagner supports the hypothesis the modularity observed in biological gene regulatory networks evolved as a result of specialization in gene activity (Espinosa-Soto & Wagner, 2010). By manipulating the implementation of their research we may further explore the conditions that drive the evolution of modularity. Specifically, this study explores how the robustness of a network and use of biased mutation may influence how modularity is evolved in gene regulatory networks.
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Totten, Mariko L., "Exploring the Evolution of Modularity in Gene Regulatory Networks" (2015). UVM Honors College Senior Theses. 69.