Supramolecular Shape-Control with Chirality-Assisted Synthesis
Little, Kassondra Marie
Little, Kassondra Marie
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Abstract
The organic world depends on proteins, which are complex polymers that have shape-determined functionality. Despite understanding the properties that dictate protein polymerization, predicting protein structure de novo remains a frontier in protein chemistry. This presentation summarizes recent advancement in chirality-assisted synthesis (CAS), a technique that accomplishes sequence-defined polymers via manipulating the chirality of the monomers. The following work describes both linear and non-linear polymers that exhibit directionality, akin to that observed in biomolecules. This has served as framework for recent work in the Schneebeli Group aimed to identify a novel, synthetic methodology that generates shape-controlled polymers.
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Date
2020-01-01
Student Status
Undergraduate
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Oral Paper Presentation
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Biochemistry
College/School
College of Arts and Sciences
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Engineering & Physical Sciences