Effects of Levonorgestrel On Breast Cancer Cell Proliferation
Berry, Sophia
Berry, Sophia
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Abstract
Breast cancer is the leading type of cancer in the U.S. among women and the second leading cause of cancer-related deaths. Women who are exposed to external hormones, through contraceptives and hormone replacement therapy, have been shown to have an increased risk for breast cancer. Levonorgestrel, a synthetic hormone found in intrauterine devices, was hypothesized to promote breast cancer viability and proliferation. To test this hypothesis, human breast cancer cells were treated with levonorgestrel plus or minus estradiol for 5 days. Compared to controls, levonorgestrel treated cells with and without estradiol, demonstrated a significant increase in cell viability and proliferation.
Description
Undergraduate
Date
2022-01-01