The Speckled Protein (SP) 110C
Cook, Elizabeth
Cook, Elizabeth
Citations
Altmetric:
License
License
Abstract
Histone post-translational modifications (PTMs) serve as an epigenetic signaling mechanism that regulates gene expression. The Speckled Protein (SP) 110C (SP110C) contains multiple functional domains such as the CARD domain that mediates the formation of larger protein complexes, along with three chromatin reader domains (SAND, plant-homeodomain, bromodomain). These reader domains bind modifications on DNA or histones and regulate cellular processes. My research aims to explore the structure and function of the SP110C SAND-PHD-BRD in recognizing histone acetylation and methylation as it is up-regulated in tamoxifen-resistant breast cancers and linked to inflammatory responses.
Description
Date
2024-01-01
Student Status
Undergraduate
Journal Title
Journal ISSN
Volume Title
Type of presentation
Poster Presentation
Collections
Research Projects
Organizational Units
Journal Issue
Citation
DOI
Advisor(s)
Department
Program/Major
Biochemistry
College/School
College of Agriculture and Life Sciences
Organization
item.page.researchcategory
Life Sciences