The role of genetic mutations in bacterial antibiotic resistance
Churchill, Madeline
Churchill, Madeline
Citations
Altmetric:
License
License
DOI
Abstract
Antibiotic resistance in bacteria has become a global epidemic, largely due to the misuse and overuse of antibiotics. Many bacteria acquire this resistance through genetic mutations, including spontaneous mutations, hypermutators, and horizontal gene transfer via conjugation, transformation, and transduction. These mutations lead to resistance by inactivating the antibiotic, modifying the target molecule, or utilizing efflux pumps. With this, studies are now focused on detecting mutations through DNA sequencing and PCR, which can improve the accuracy of diagnoses, guide appropriate antibiotic prescriptions, and lead to more effective treatment plans.
Description
Undergraduate
Date
2025-05-29