Therapeutic Potential of Novel TRPV4 Endothelial Leakiness
Roode, Nicole
Roode, Nicole
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Abstract
In biomedical applications, the effects of nanoparticles on human cells and tissues are not fully understood. One principal area of study is focused on the interactions between nanoparticles and the endothelial layer, the cellular barrier between blood flow and the extravascular tissues. The Biomedical Nanotechnology and Biomaterials Lab recently demonstrated that there are size-specific impacts of nanoparticles on the endothelial barrier especially of the 20 nm inorganic particles. I propose to study the impact of 20 nm particles on the passage of a polydisperse sample through the endothelial layer to examine the potential for future drug delivery applications.
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Graduate
Date
2023-01-01