Investigating the Protein-Coding Potential of a lncRNA
Varnum, Stella
Varnum, Stella
Citations
Altmetric:
License
License
DOI
Abstract
Study in the field of genetics has identified long non-coding RNA (lncRNA) as a novel class of molecule that participates in cell function in diverse and convoluted ways. The mouse gene U90926 is thought to produce one such lncRNA molecule in activated macrophage cells. Macrophage activation is a key component of the inflammatory response, and is known to influence the onset of autoimmune disorders. My project investigates the protein-coding potential of U90926. Characterization of the molecule(s) produced by this gene will indicate its mechanistic role in regulating macrophage activation. Improved understanding of how this process influences the larger immune response could prompt innovation of new therapies for autoimmune diseases.
Description
3:00pm-5:00pm
Undergraduate
Undergraduate
Date
2020-01-01