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The role of pharmacogenetics in adverse drug reactions

Wermter, Mary
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Abstract
Pharmacogenetics examines how genetic variations influence drug response, focusing on pharmacokinetics (drug absorption, distribution, metabolism, and excretion) and pharmacodynamics (drug effects on the body). By analyzing genetic differences that alter drug interactions, pharmacogenetics helps predict individual variations in drug metabolism and response, potentially identifying adverse drug reactions (ADRs) linked to single nucleotide polymorphisms (SNPs). The PREPARE study demonstrated the clinical benefits of pharmacogenetic panel implementation, showing its potential to reduce ADR severity and occurrence. These findings highlight the future role of pharmacogenetics in personalized medicine, improving drug safety and efficacy.
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Date
2025-05-29
Student Status
Undergraduate
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Type of presentation
Poster Presentation
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UVM Student Research Conference
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URI
https://hdl.handle.net/20.500.14849/8933
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Advisor(s)
Melissa Pespeni
Department
Program/Major
Biology
College/School
College of Arts and Sciences
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Life Sciences
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