Spatial and Working Memory in Mice post Traumatic Brain Injury
Baumann, Sarah
Baumann, Sarah
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Abstract
This study seeks to illuminate the effects of traumatic brain injuries (TBI) on the spatial and working memory of mice. It is hypothesized that three sequential low-level blast waves will impair the spatial memory capabilities of mice compared to uninjured mice. Mice first train on a spatial accuracy task based on automated food rewards, are then given three mild TBI, followed by testing on the accuracy task again. The mice with a TBI had interference of their working memory and had trouble differentiating between the correct goal areas compared to controls. This data can be used to determine cognitive differences in individuals with a blast injury.
Description
Undergraduate
Date
2023-01-01