Effect of Cystic Fibrosis treatment drugs on lung-specific cell toxicity
Mahdi, Sama A
Mahdi, Sama A
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Abstract
The work I started during my fellowship addressed whether two Cystic Fibrosis (CF) treatments, Tezacaftor and Ivacaftor, lead to toxicity in human lung-specific cell types, such as bronchial epithelial (HBE) cells. Some of the work had been already completed. My particular task was to work with HBE cells. I learned tissue culturing techniques and experimental design and then did a trial run, without drug treatment, to master the assay techniques. Although I will finalize the work this summer, my fellowship experience has been invaluable and will help me complete a critical experiment by assessing the toxicity of these CF drugs.
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Date
2022-01-01
Student Status
Undergraduate
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Poster Presentation
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Biomedical Engineering
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College of Engineering and Mathematical Sciences
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Biological Sciences