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The OPRM1 gene: The powerhouse of pain killers

Estrella, Nathan
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Abstract
Prior research has identified the OPRM1 gene as a factor in genetic dispositions to addiction. This gene is responsible for the production of mu-opioid receptors, which are used to modulate pain in the nervous system. The authors sought to identify the outcomes of single nucleotide polymorphisms (SNPs) of the OPRM1 gene. They found that the homozygous recessive genotype is less common and that this genotype resulted in a SNP that inhibited OPRM1 function. These findings provide a better understanding of how genetics and addiction tend to influence one another.
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Date
2025-05-29
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Undergraduate
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Biology
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College of Arts and Sciences
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Life Sciences
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