Presentation Title

Persistent Postural Perceptual Dizziness (PPPD): Diagnostics and Mechanisms of Action

Project Collaborators

Dr. Sambit Mohapatra, Dr. George Kurien

Abstract

INTRODUCTION: Persistent postural perceptual dizziness (PPPD) is a chronic dysfunction of the integration between the vestibular system and brain that results in persistent dizziness, non-spinning vertigo, and unsteadiness. This disorder constitutes a long-term maladaptation to a repetitive neuro-otological, medical, or psychological event that triggers irregular vestibular symptoms. Current diagnostic tests are unable to produce consistent diagnoses within patients with PPPD and thus lack a gold-standard. The purpose of this scoping review was to: i) evaluate current diagnostic guidelines and develop more consistent diagnostic testing options for patients with PPPD, and ii) identify gaps in literature that could inform future clinical evaluations for clinicians. METHODS: Ovid Medline, PubMed, PsychInfo, and CINAHL databases were searched for published research articles after 2014. “Persistent postural perceptual dizziness” was used as the primary search term. Diagnostic reports, clinical evaluations, and preliminary research studies were included with systematic literature reviews and any treatment or intervention studies being excluded. RESULTS: Preliminary searches generated 199 results. After initial examination using the inclusion criteria and after removing duplicates 45 articles were included. Ongoing analysis is being currently conducted.

Primary Faculty Mentor Name

Dr. Sambit Mohapatra

Secondary Mentor NetID

George.Kurien@uvmhealth.org

Secondary Mentor Name

Dr. George Kurien

Status

Graduate

Student College

College of Nursing and Health Sciences

Program/Major

Human Functioning and Rehabilitation Science

Primary Research Category

Health Sciences

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Persistent Postural Perceptual Dizziness (PPPD): Diagnostics and Mechanisms of Action

INTRODUCTION: Persistent postural perceptual dizziness (PPPD) is a chronic dysfunction of the integration between the vestibular system and brain that results in persistent dizziness, non-spinning vertigo, and unsteadiness. This disorder constitutes a long-term maladaptation to a repetitive neuro-otological, medical, or psychological event that triggers irregular vestibular symptoms. Current diagnostic tests are unable to produce consistent diagnoses within patients with PPPD and thus lack a gold-standard. The purpose of this scoping review was to: i) evaluate current diagnostic guidelines and develop more consistent diagnostic testing options for patients with PPPD, and ii) identify gaps in literature that could inform future clinical evaluations for clinicians. METHODS: Ovid Medline, PubMed, PsychInfo, and CINAHL databases were searched for published research articles after 2014. “Persistent postural perceptual dizziness” was used as the primary search term. Diagnostic reports, clinical evaluations, and preliminary research studies were included with systematic literature reviews and any treatment or intervention studies being excluded. RESULTS: Preliminary searches generated 199 results. After initial examination using the inclusion criteria and after removing duplicates 45 articles were included. Ongoing analysis is being currently conducted.