First identified in Uganda in 1947, the Zika virus simmered quietly for sixty years, occasionally causing a mild dengue-like illness across parts of central Africa and equatorial Asia. However, since 2007, three large outbreaks have occurred: first in Micronesia, then in French Polynesia in 2013-2014, and as an epidemic involving Mexico, the Caribbean, and Central and South America in 2015-2016. This paper reviews the virology of the Zika virus, its modes of transmission, symptoms of Zika Virus Disease, the association of Zika infections with microcephaly and Guillain-Barre Syndrome, prevention of Zika infections, and ongoing efforts to develop a vaccine.


This is an Accepted Manuscript of an article published by Taylor & Francis in Science & Technology Libraries on June 24, 2016, available at http://www.tandfonline.com/doi/full/10.1080/0194262X.2016.1192007.


Zika virus, arbovirus, microcephaly, Aedes aegypti, Guillain-Barre

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Taylor & Francis