Retrospective Analysis of Cutaneous Squamous Cell Carcinoma of the Lip Treated at the University of Vermont Medical Center
Conference Year
January 2019
Abstract
The overall goal of the project is to assess outcomes after Moh’s surgery for the treatment of cutaneous squamous cell carcinoma (cSCC). Moh’s micrographic surgery is a specialized method of removing skin cancer and aims to achieve the maximum likelihood of cure while removing the minimum amount of skin. It does this by taking horizontal cuts of the tissue and mounting the specimen in such a way as to allow for histologic inspection of one hundred percent of the surgical margin. If cancer cells remain visible at the margin, the surgeon resects additional tissue only from the corresponding location on the patient’s skin and repeats this process until the margins are clear of malignancy. This is in contrast to a standard wide local excision where the sample is sectioned vertically by “breadloafing” and less than one percent of the margins are visible for analysis. We aim to assess cSCC outcomes in patients who undergo Moh’s surgical excision.
Primary Faculty Mentor Name
Melanie Bui
Status
Medical Students
Student College
Larner College of Medicine
Program/Major
Biological Sciences, Integrated
Primary Research Category
Health Sciences
Retrospective Analysis of Cutaneous Squamous Cell Carcinoma of the Lip Treated at the University of Vermont Medical Center
The overall goal of the project is to assess outcomes after Moh’s surgery for the treatment of cutaneous squamous cell carcinoma (cSCC). Moh’s micrographic surgery is a specialized method of removing skin cancer and aims to achieve the maximum likelihood of cure while removing the minimum amount of skin. It does this by taking horizontal cuts of the tissue and mounting the specimen in such a way as to allow for histologic inspection of one hundred percent of the surgical margin. If cancer cells remain visible at the margin, the surgeon resects additional tissue only from the corresponding location on the patient’s skin and repeats this process until the margins are clear of malignancy. This is in contrast to a standard wide local excision where the sample is sectioned vertically by “breadloafing” and less than one percent of the margins are visible for analysis. We aim to assess cSCC outcomes in patients who undergo Moh’s surgical excision.