Decreased ability to extinguish conditioned fear response as a predictor of impulsivity in adults with Post Traumatic Stress Disorder

Abstract

25% of people who experience a potentially traumatic event (PTE) develop Post Traumatic Stress Disorder (PTSD) within 12 months (Zatzick et al., 2007). Individuals with PTSD face an increased risk for engaging in impulsive behaviors; the presence of these behaviors exacerbates impairments associated with PTSD and complicate the treatment and recovery (Roley et al., 2017) (Goldstein et al., 2016). Using statistical methods, the present project examines the associations between difficulty extinguishing fear-potentiated startle response with increased impulsivity among adults with PTSD. An association is expected between increased impulsive behaviors and decreased ability to inhibit learned fear within adults with PTSD.

Goldstein, R. B., Smith, S. M., Chou, S. P., Saha, T. D., Jung, J., Zhang, H., Pickering, R. P., Ruan, W. J., Huang, B., & Grant, B. F. (2016). The Epidemiology of DSM-5 Posttraumatic Stress Disorder in the United States: Results from the National Epidemiologic Survey on Alcohol and Related Conditions-III. Social Psychiatry and Psychiatric Epidemiology, 51(8), 1137–1148. https://doi.org/10.1007/s00127-016-1208-5

Roley, M. E., Contractor, A. A., Weiss, N. H., Armour, C., & Elhai, J. D. (2017). Impulsivity facets’ predictive relations with DSM-5 PTSD symptom clusters. Psychological Trauma : Theory, Research, Practice and Policy, 9(1), 76–79. https://doi.org/10.1037/tra0000146

Zatzick, D. F., Rivara, F. P., Nathens, A. B., Jurkovich, G. J., Wang, J., Fan, M.-Y., Russo, J., Salkever, D. S., & Mackenzie, E. J. (2007). A nationwide US study of post-traumatic stress after hospitalization for physical injury. Psychological Medicine, 37(10), 1469–1480. https://doi.org/10.1017/S0033291707000943

Primary Faculty Mentor Name

Matthew Price

Status

Undergraduate

Student College

College of Arts and Sciences

Program/Major

Neuroscience

Primary Research Category

Arts & Humanities

Abstract only.

Share

COinS
 

Decreased ability to extinguish conditioned fear response as a predictor of impulsivity in adults with Post Traumatic Stress Disorder

25% of people who experience a potentially traumatic event (PTE) develop Post Traumatic Stress Disorder (PTSD) within 12 months (Zatzick et al., 2007). Individuals with PTSD face an increased risk for engaging in impulsive behaviors; the presence of these behaviors exacerbates impairments associated with PTSD and complicate the treatment and recovery (Roley et al., 2017) (Goldstein et al., 2016). Using statistical methods, the present project examines the associations between difficulty extinguishing fear-potentiated startle response with increased impulsivity among adults with PTSD. An association is expected between increased impulsive behaviors and decreased ability to inhibit learned fear within adults with PTSD.

Goldstein, R. B., Smith, S. M., Chou, S. P., Saha, T. D., Jung, J., Zhang, H., Pickering, R. P., Ruan, W. J., Huang, B., & Grant, B. F. (2016). The Epidemiology of DSM-5 Posttraumatic Stress Disorder in the United States: Results from the National Epidemiologic Survey on Alcohol and Related Conditions-III. Social Psychiatry and Psychiatric Epidemiology, 51(8), 1137–1148. https://doi.org/10.1007/s00127-016-1208-5

Roley, M. E., Contractor, A. A., Weiss, N. H., Armour, C., & Elhai, J. D. (2017). Impulsivity facets’ predictive relations with DSM-5 PTSD symptom clusters. Psychological Trauma : Theory, Research, Practice and Policy, 9(1), 76–79. https://doi.org/10.1037/tra0000146

Zatzick, D. F., Rivara, F. P., Nathens, A. B., Jurkovich, G. J., Wang, J., Fan, M.-Y., Russo, J., Salkever, D. S., & Mackenzie, E. J. (2007). A nationwide US study of post-traumatic stress after hospitalization for physical injury. Psychological Medicine, 37(10), 1469–1480. https://doi.org/10.1017/S0033291707000943