The Role of Crk and Crkl Adaptor Proteins in the hair cells of Danio rerio inner ear and lateral line
Conference Year
January 2022
Abstract
The adaptor proteins Crk and Crkl are important regulators of cell migration, particularly in the layers of the Central Nervous System. They have also been identified, through in situ hybridization in the organism Danio rerio, to be present in the sensory hair cells of the inner ear. Their role in this location, and in other sensory hair cells along the zebrafish lateral line, is unknown. This project seeks to understand the function of Crk and Crkl in hair cell development and migration along the lateral line by examining the structure and location of lateral line organs, known as neuromasts.
Primary Faculty Mentor Name
Alicia Ebert
Graduate Student Mentors
Helaina Stergas
Status
Undergraduate
Student College
College of Arts and Sciences
Program/Major
Neuroscience
Primary Research Category
Biological Sciences
The Role of Crk and Crkl Adaptor Proteins in the hair cells of Danio rerio inner ear and lateral line
The adaptor proteins Crk and Crkl are important regulators of cell migration, particularly in the layers of the Central Nervous System. They have also been identified, through in situ hybridization in the organism Danio rerio, to be present in the sensory hair cells of the inner ear. Their role in this location, and in other sensory hair cells along the zebrafish lateral line, is unknown. This project seeks to understand the function of Crk and Crkl in hair cell development and migration along the lateral line by examining the structure and location of lateral line organs, known as neuromasts.