Effects of isoleucine on the biosynthesis of branched-chain fatty acids by ruminal microorganisms

Conference Year

January 2022

Abstract

The objective of this study was to evaluate increasing doses of isoleucine, the metabolic precursor of the BCFAs anteiso-15:0 and anteiso-17:0, by ruminal microorganisms in vitro. Four single-flow continuous culture fermenters were utilized in a 4 X 4 Latin square design. Treatments consisted of 0.65 g isoleucine/day (baseline amount in the diet), 1.30 g/day, 1.95 g/day and 2.60 g/day. Bacterial and protozoal cell fractions were isolated from rumen fluid contents, and BCFA content of their lipid membranes was determined via gas-liquid chromatography. Our results provide direct evidence that rumen bacteria and protozoa use isoleucine as a precursor for anteiso-15:0.

Primary Faculty Mentor Name

Dr. Jana Kraft

Faculty/Staff Collaborators

Dr. Sabrina Greenwood

Status

Graduate

Student College

College of Agriculture and Life Sciences

Program/Major

Animal, Nutrition and Food Sciences

Primary Research Category

Biological Sciences

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Effects of isoleucine on the biosynthesis of branched-chain fatty acids by ruminal microorganisms

The objective of this study was to evaluate increasing doses of isoleucine, the metabolic precursor of the BCFAs anteiso-15:0 and anteiso-17:0, by ruminal microorganisms in vitro. Four single-flow continuous culture fermenters were utilized in a 4 X 4 Latin square design. Treatments consisted of 0.65 g isoleucine/day (baseline amount in the diet), 1.30 g/day, 1.95 g/day and 2.60 g/day. Bacterial and protozoal cell fractions were isolated from rumen fluid contents, and BCFA content of their lipid membranes was determined via gas-liquid chromatography. Our results provide direct evidence that rumen bacteria and protozoa use isoleucine as a precursor for anteiso-15:0.