Effects of Different Types of Alcohol Withdrawal on Hepatic Triglyceride Content in Mice

Presenter's Name(s)

Virginia Clubb

Conference Year

2024

Abstract

Alcohol consumption is known to induce liver damage, with most research focusing on chronic alcohol use. However, questions persist regarding the impact of alcohol withdrawal on liver fat content. To address this, we administered differing alcohol withdrawal treatments to female C57BL/6 mice: continuous access, 4-day withdrawal, or 24-hour withdrawal. Our study aims to determine the influence of withdrawal duration on liver health indicators using a standard triglyceride assay. This research seeks to elucidate the relationship between alcohol withdrawal and liver health outcomes, which is part of a broader focus of the RAMP lab involving hepatic diet and alcohol interactions.

Primary Faculty Mentor Name

Chris Skinner

Status

Undergraduate

Student College

College of Agriculture and Life Sciences

Program/Major

Nutrition and Food Sciences

Primary Research Category

Life Sciences

Abstract only.

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Effects of Different Types of Alcohol Withdrawal on Hepatic Triglyceride Content in Mice

Alcohol consumption is known to induce liver damage, with most research focusing on chronic alcohol use. However, questions persist regarding the impact of alcohol withdrawal on liver fat content. To address this, we administered differing alcohol withdrawal treatments to female C57BL/6 mice: continuous access, 4-day withdrawal, or 24-hour withdrawal. Our study aims to determine the influence of withdrawal duration on liver health indicators using a standard triglyceride assay. This research seeks to elucidate the relationship between alcohol withdrawal and liver health outcomes, which is part of a broader focus of the RAMP lab involving hepatic diet and alcohol interactions.