Pilots of Western diet and binge drinking: Effects on the mouse brain
Abstract
Western Diet is linked to neurodegenerative diseases and negative brain health outcomes while binge drinking can cause neurodegeneration without any nutritional deficiency. Yet, the combination of these two together, commonly seen amongst college students, and their impacts on the brain are poorly understood. Here, 8-week-old mice were assigned to one of eight groups: male/female AIN, AIN+Binge, Western, or Western+Binge. Enzymatic assays were used to measure brain health following 12 weeks of treatment. Results are forthcoming but preliminary data indicates distinct sex differences, and that binge drinking has no further detriment on brain health in the presence of western diet.
Primary Faculty Mentor Name
Chris Skinner
Status
Undergraduate
Student College
College of Arts and Sciences
Program/Major
Biology
Primary Research Category
Life Sciences
Pilots of Western diet and binge drinking: Effects on the mouse brain
Western Diet is linked to neurodegenerative diseases and negative brain health outcomes while binge drinking can cause neurodegeneration without any nutritional deficiency. Yet, the combination of these two together, commonly seen amongst college students, and their impacts on the brain are poorly understood. Here, 8-week-old mice were assigned to one of eight groups: male/female AIN, AIN+Binge, Western, or Western+Binge. Enzymatic assays were used to measure brain health following 12 weeks of treatment. Results are forthcoming but preliminary data indicates distinct sex differences, and that binge drinking has no further detriment on brain health in the presence of western diet.
