Expanding the phosphine source in hydrophosphination: An exploration into phosphine electronics in P–C bond forming reactions
Abstract
Hydrophosphination is an atom–economical way to form phosphorus–carbon bonds. Phosphines have highly tunable steric and electronic properties which makes them ideal for exploratory hydrophosphination. Cu(acac)2 is a general precatalyst for hydrophosphination, aided by photochemical conditions, and is highly active for alkenes. Several diaryl phosphines will be synthesized, with varying substituents in the parasubstituted position. Understanding how adjusting the electronics at phosphorus could tune the chromophore allows for a deeper understanding of phosphorus chemistry. Furthermore, hydrophosphination with a variety of phosphines will yield novel, highly sought after products. These novel phosphines have also shown promise as useful organometallic ligands.
Primary Faculty Mentor Name
Rory Waterman
Status
Undergraduate
Student College
College of Arts and Sciences
Program/Major
Chemistry
Primary Research Category
Physical Science
Expanding the phosphine source in hydrophosphination: An exploration into phosphine electronics in P–C bond forming reactions
Hydrophosphination is an atom–economical way to form phosphorus–carbon bonds. Phosphines have highly tunable steric and electronic properties which makes them ideal for exploratory hydrophosphination. Cu(acac)2 is a general precatalyst for hydrophosphination, aided by photochemical conditions, and is highly active for alkenes. Several diaryl phosphines will be synthesized, with varying substituents in the parasubstituted position. Understanding how adjusting the electronics at phosphorus could tune the chromophore allows for a deeper understanding of phosphorus chemistry. Furthermore, hydrophosphination with a variety of phosphines will yield novel, highly sought after products. These novel phosphines have also shown promise as useful organometallic ligands.
