Cardiolipin and CD1d in Innate-like T Cell Activation

Presenter's Name(s)

Remi Savard, UVMFollow

Abstract

Cardiolipin (CL) is a mitochondrial lipid proposed to function as cellular stress signal and innate-like T cell autoantigen. Our research shows limited activation of iNKT cells to produce cytokine after CL stimulation.

Primary Faculty Mentor Name

Jonathan Boyson

Secondary Mentor Name

Oliver Dienz

Graduate Student Mentors

Somen K. Mistri

Status

Undergraduate

Student College

College of Agriculture and Life Sciences

Program/Major

Microbiology

Primary Research Category

Biological Sciences

Secondary Research Category

Health Sciences

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Cardiolipin and CD1d in Innate-like T Cell Activation

Cardiolipin (CL) is a mitochondrial lipid proposed to function as cellular stress signal and innate-like T cell autoantigen. Our research shows limited activation of iNKT cells to produce cytokine after CL stimulation.