Efficient Precatalysts for Silicon-Nitrogen Heterodehydrocoupling
Conference Year
2024
Abstract
Aminosilanes and silyamines have a wide range of applications from protecting groups in synthesis to ceramic precursors. Silicon-nitrogen heterodehydrocoupling is a versatile catalytic method to form these Si-N bonds. The atom-economy and greenness of heterodehydrocoupling makes this reaction attractive, and as such search for effective catalysts has been ongoing. Several commercially available compounds have been found to be effective silicon-nitrogen heterodehydrocoupling precatalysts including n BuLi, KOt Amyl, and MeMgBr. Substrate scope of these catalysts have shown short reaction times under mild conditions for a variety of silanes and amines used. These catalyst investigations will lead to more accessible and cost-effect Si-N heterodehydrocoupling.
Primary Faculty Mentor Name
Rory Waterman
Graduate Student Mentors
Diego Javier-Jimenez, Dr. Matthew Reuter
Status
Undergraduate
Student College
College of Arts and Sciences
Second Student College
Patrick Leahy Honors College
Program/Major
Chemistry
Primary Research Category
Physical Science
Efficient Precatalysts for Silicon-Nitrogen Heterodehydrocoupling
Aminosilanes and silyamines have a wide range of applications from protecting groups in synthesis to ceramic precursors. Silicon-nitrogen heterodehydrocoupling is a versatile catalytic method to form these Si-N bonds. The atom-economy and greenness of heterodehydrocoupling makes this reaction attractive, and as such search for effective catalysts has been ongoing. Several commercially available compounds have been found to be effective silicon-nitrogen heterodehydrocoupling precatalysts including n BuLi, KOt Amyl, and MeMgBr. Substrate scope of these catalysts have shown short reaction times under mild conditions for a variety of silanes and amines used. These catalyst investigations will lead to more accessible and cost-effect Si-N heterodehydrocoupling.