Utilizing Biomaterials to Mimic Lung Diseases and Understand Cellular Repair Mechanisms
Conference Year
2024
Abstract
Idiopathic Pulmonary Fibrosis (IPF) affects roughly 250,000 globally with a 3-5 year survival rate after being diagnosed and no cure. There is a significant gap in the knowledge surrounding cellular and molecular lung repair which in turn has delayed advancement of therapeutic approaches for IPF. The implementation of novel human lung-derived biomaterials that mimic physiological pathways in lung diseases allows us to more effectively track cell repair behavior in experimental conditions. Pursuing this aspect of basic physiology can provide further insight into inflammatory and interstitial pulmonary diseases and future treatment therapeutic strategies.
Primary Faculty Mentor Name
Daniel Weiss
Status
Undergraduate
Student College
College of Nursing and Health Sciences
Second Student College
Larner College of Medicine
Program/Major
Exercise Science
Primary Research Category
Life Sciences
Utilizing Biomaterials to Mimic Lung Diseases and Understand Cellular Repair Mechanisms
Idiopathic Pulmonary Fibrosis (IPF) affects roughly 250,000 globally with a 3-5 year survival rate after being diagnosed and no cure. There is a significant gap in the knowledge surrounding cellular and molecular lung repair which in turn has delayed advancement of therapeutic approaches for IPF. The implementation of novel human lung-derived biomaterials that mimic physiological pathways in lung diseases allows us to more effectively track cell repair behavior in experimental conditions. Pursuing this aspect of basic physiology can provide further insight into inflammatory and interstitial pulmonary diseases and future treatment therapeutic strategies.