Mooving Along: Determining Distance traveled by Cryptosporidium parvum Sporozoites and Merozoites before Infecting a Cell

Presenter's Name(s)

Emmett DewsFollow

Conference Year

January 2022

Abstract

Cryptosporidium is a parasite that causes life threatening and chronic diarrhea in children and immuno-compromised individuals. Chronic infections occur as Cryptosporidium auto-infects the same host and serves as a potential source of genetic variation for the rise of drug resistance. Despite this impediment to drug development, little is known. The end goal is the development of a computer program that can model the evolution of Cryptospordium during an infection that incorporates sexual recombination. Before this goal is realized, the movement of Cryptosporidium needs to be understood. This experiment looked to observe and quantify the movement of Cryptosporidium parvum as sporozoites and merozoites.

Primary Faculty Mentor Name

Christopher Huston

Status

Undergraduate

Student College

College of Agriculture and Life Sciences

Program/Major

Microbiology

Second Program/Major

Pharmacology

Primary Research Category

Health Sciences

Secondary Research Category

Biological Sciences

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Mooving Along: Determining Distance traveled by Cryptosporidium parvum Sporozoites and Merozoites before Infecting a Cell

Cryptosporidium is a parasite that causes life threatening and chronic diarrhea in children and immuno-compromised individuals. Chronic infections occur as Cryptosporidium auto-infects the same host and serves as a potential source of genetic variation for the rise of drug resistance. Despite this impediment to drug development, little is known. The end goal is the development of a computer program that can model the evolution of Cryptospordium during an infection that incorporates sexual recombination. Before this goal is realized, the movement of Cryptosporidium needs to be understood. This experiment looked to observe and quantify the movement of Cryptosporidium parvum as sporozoites and merozoites.